When cells do not properly interact or improperly ode molecular messages, disease HHS. Direct interactions between cells, as well as between cells and the extracellular matrix, are critical to the development and function of multicellular organisms. First, cells exhibit excluded volume (EV) interactions, where an individual cell occupies space and exerts a repelling force on other cells that move within this space (17) Cell Cell–cell interactions orchestrate organismal development, homeostasis a