Various genetic mutations cause the condition. ,  · Introduction: situs inversus is a rare congenital anomaly characterized by the transposition of the abdominal organs, viscera and vasculature, in relation to the Situs inversus is a rare genetic condition in which the organs in your chest and abdomen are positioned in a mirror image of normal human anatomy. Situs inversus can develop on its own, but it’s often linked with other defects or issues. Nearly all of the organs in Missing: pdf Situs